Background Behavioral criteria that confirm neuropathic pain in animal injury models are
undefined. Therefore, the authors sought clinically relevant measures that distinguish pain
behavior of rats with peripheral nerve injury from those with sham injury. Methods The
authors examined mechanical and thermal sensory sensitivity, comparing responses at
baseline to responses after spinal nerve ligation (SNL group), sham nerve injury (sham
group), or skin incision alone (control group). Results Substantial variance was evident in all …